ONE & ONLY CURCUMIN POWDER WITH ENHANCED FREE CURCUMINOIDS
CurQfen® is a “Spiceuticals – curcumin” developed by several years of our constant R&D efforts. The unique delivery mechanism of CurQfen® and its enhanced efficacy with regard to brain, heart, joints & liver health has been clinically evaluated and published in highly cited journals with high impact factors. It is the SCIENCE that distinguishes CurQfen® from the other bioavailable formulations of curcumin. Novel delivery mechanism, ability to provide bioactive free-form curcuminoids for longer duration with cellular uptake and improved blood-brain-barrier permeability are the key factors of CurQfen®. It is the one and only form of curcumin powder that has been investigated to enhance free curcuminoids bioavailability in human subjects and the measurement of the ratio of free-form curcumin to the biologically inactive curcumin glucoronides.
The unique delivery mechanism of CurQfen® and its enhanced efficacy with regard to brain, heart, joints & liver health has been clinically evaluated and published in highly cited journals with high impact factors. It is the SCIENCE that distinguishes CurQfen® from the other bioavailable formulations of curcumin. Novel delivery mechanism, ability to provide bioactive free-form curcuminoids for longer duration with cellular uptake and improved blood-brain-barrier permeability are the key factors of CurQfen®. It is the one and only form of curcumin powder which has been investigated to enhanced free curcuminoids bioavailability in human subjects and the measurement of the ratio of free-form curcumin to the biologically inactive curcumin glucoronides.
Journal of Toxicology, 2021
Study period – 90 days
No of subjects – 34
Dosage – 1000mg/day
Result – CurQfen® was found to be safe curcumin supplement for regular consumption and is devoid of any adulterants and contaminants.
Journal of functional foods 22 ( 2016 ) 578–587
No of subjects – 50
Dosage – 250-1000mg
Result – CGM administration provided over 45.5-fold enhancement in free curcuminoids bioavailability with improved pharmacokinetics.
Journal of functional foods 14 ( 2 0 1 5 ) 215–225
No of subjects – 54 male wistar rats
Dosage – 200mg
Result – Post administration tissue samples of Wistar rats demonstrated significant enhancement in plasma bioavailability in vivo stability and blood–brainbarrier permeability as evidenced from the tissue distribution of free curcuminoids.
Journal of Nutritional Neuroscience, 2021
No of subjects – 48 male wistar rats
Dosage – 100mg
Result – CurQfen® was able to distribute significant amount of free curcuminoids, in brain especially in the hippocampus. Administration of CurQfen® also shown positive impact in behavior of animals.
Journal of Clinical Psychopharmacology, 2016
Dosage – 1000mg
Result – A significant reduction in stress, anxiety and fatigue leading to a better quality of life was observed for CurQfen® administered participants
Journal of Nutritional Neuroscience, 2020
No of subjects – 18
Dosage – 500mg
Result – Supplementation of CGM resulted in a significant increase in α- andβ-waves, a significant reduction in α/β ratio in comparison with unformulated curcumin and significant reduction in the audio-reaction time.
Journal of Alternative and complementary medicine, 2020; 1-11
No of subjects – 80
Dosage – 400mg x2/day
Result – Curcumagalactomannoside/Glucosamine was found to offer significant beneficial effects to pain, stiffness, and physical function of OA subjects compared with CHN-GLN, which was evident from the improvement in walking performance, VAS score, KPS score, and WOMAC score.
Journal of Phytotherapy Research, 2020; 1-13
No of subjects – 72
Dosage – 400mg/ day
Result – CGM exhibited 47.02, 21.43, and 206% improvement in VAS, KPS, and walking performance, respectively, compared to the baseline.
Rheumatology: Current Research, 2021
No of subjects – Male Wistar rats
Dosage – 100mg/kg b.wt.
Result – CurQfen® was found to have antioxidant, anti-inflammatory and anti-arthritic activity in the experimental arthritic model.
Curcumin-Galactomannoside Complex inhibits the Proliferation
of Human Cervical Cancer Cells: Possible Role in Cell Cycle
Arrest and Apoptosis
Asian Pacific Journal of Cancer Prevention, 2021
Conclusion: CurQfen® is a potent and promising natural formulation against cervical cancer cells via induction of apoptosis through ROS mediated mitochondrial damage in HeLa cells.
Life sciences, 2021
No of subjects – Twelve female BALB/c mice
Dosage – 100 mg/kg b.wt.
Result – CurQfen® has high potential in the prevention and treatment of multiple chronic diseases.
Amelioration of Radiation-Induced Damages in Mice by Curcuminoids: The Role of Bioavailability
Journal of Nutrition and cancer, 2020
No of subjects – 48 male swiss albino mice/ 24 male swiss albino mice
Dosage – 100mg
Result – Oral administration of CurQfen® was found to provide better clastogenic and genotoxic potential
Ameliorating demyelination effect of curqfen® in cuprizone induced mice model of multiple sclerosis
International Journal of Pharmacy and Pharmacology, 2019
No of subjects –
Dosage – 200mg / 400mg
Result – CurQfen® at dosage of 400mg exhibited significant neuroprotection and remyelination.
Journal of Pharmacognosy and Natural Products, 2019
No of subjects –
Dosage – 200mg
Result – CurQfen® possesses significant enhanced cognitive effects than unformulated curcumin (IEAC No: DPS/12/2015)
Journal of Nutrition, 2019
No of subjects – 22 Men
Dosage – 500mg/day
Result – CurQfen® improves homocysteine and high-density lipoprotein concentrations, which may promote favorable cardiovascular health.
Journal of Biochemical and Molecular Toxicology, 2019
No of subjects – 32 male wistar rats
Dosage – 250 mg/kg b.w
Result – Supplementation of CurQfen®reversed all of the pathological effects of alcohol administration, almost close to the normal level, when compared with unformaulated curcumin.
Natural Product Research, 2018
No of subjects –
Dosage – 250mg
Result – CurQfen® was more effective in mitigating carbofuran toxicity with results comparable to that of normal curcumin.
Journal of Inflammopharmacology, 2018
No of subjects –
Dosage –
Result – CurQfen® has significant anti-inflammatory effect on ox-LDL induced inflammatory condition.
Journal of BioMed Research International, 2018
No of subjects – 48
Dosage – 500mg
Result – CurQfen® was found to offer significant hepatoprotective effect towards the alcohol induced alterations to hepatic function markers.
Journal of functional foods, 2017
No of subjects – 22
Dosage – 500mg
Result – CurQfen® was found to have the potential to de-stiffen arteries in young, obese men with greater aortic stiffness